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Proteomic Mapping of Mitochondria in Living Cells via Spatially-Restricted Enzymatic Tagging

Microscopy and mass spectrometry (MS) are complementary techniques: the former provides spatiotemporal information in living cells, but only for a handful of recombinant proteins, while the latter can detect thousands of endogenous proteins simultaneously, but only in lysed samples. Here we introduc...

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Autori principali: Rhee, Hyun-Woo, Zou, Peng, Udeshi, Namrata D., Martell, Jeffrey D., Mootha, Vamsi K., Carr, Steven A., Ting, Alice Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916822/
https://ncbi.nlm.nih.gov/pubmed/23371551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1230593
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