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Strand-specific Recognition of DNA Damages by XPD Provides Insights into Nucleotide Excision Repair Substrate Versatility

Recognition and removal of DNA damages is essential for cellular and organismal viability. Nucleotide excision repair (NER) is the sole mechanism in humans for the repair of carcinogenic UV irradiation-induced photoproducts in the DNA, such as cyclobutane pyrimidine dimers. The broad substrate versa...

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Detalhes bibliográficos
Main Authors: Buechner, Claudia N., Heil, Korbinian, Michels, Gudrun, Carell, Thomas, Kisker, Caroline, Tessmer, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916561/
https://ncbi.nlm.nih.gov/pubmed/24338567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523001
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