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Characterization of the Deubiquitinating Activity of USP19 and Its Role in Endoplasmic Reticulum-associated Degradation

Deubiquitinating enzymes (DUBs) regulate various cellular processes ranging from protein degradation to cellular signaling. USP19, the only DUB containing a carboxyl-terminal transmembrane domain, was proposed to function in endoplasmic reticulum-associated degradation (ERAD). Here we characterize t...

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Bibliografiske detaljer
Main Authors: Lee, Jin-Gu, Kim, Woong, Gygi, Steven, Ye, Yihong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916552/
https://ncbi.nlm.nih.gov/pubmed/24356957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.538934
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