Novel Structural Features in Candida albicans Hyphal Glucan Provide a Basis for Differential Innate Immune Recognition of Hyphae Versus Yeast

The innate immune system differentially recognizes Candida albicans yeast and hyphae. It is not clear how the innate immune system effectively discriminates between yeast and hyphal forms of C. albicans. Glucans are major components of the fungal cell wall and key fungal pathogen-associated molecula...

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Detalhes bibliográficos
Main Authors: Lowman, Douglas W., Greene, Rachel R., Bearden, Daniel W., Kruppa, Michael D., Pottier, Max, Monteiro, Mario A., Soldatov, Dmitriy V., Ensley, Harry E., Cheng, Shih-Chin, Netea, Mihai G., Williams, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916545/
https://ncbi.nlm.nih.gov/pubmed/24344127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529131
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