Novel Structural Features in Candida albicans Hyphal Glucan Provide a Basis for Differential Innate Immune Recognition of Hyphae Versus Yeast

The innate immune system differentially recognizes Candida albicans yeast and hyphae. It is not clear how the innate immune system effectively discriminates between yeast and hyphal forms of C. albicans. Glucans are major components of the fungal cell wall and key fungal pathogen-associated molecula...

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Autori principali: Lowman, Douglas W., Greene, Rachel R., Bearden, Daniel W., Kruppa, Michael D., Pottier, Max, Monteiro, Mario A., Soldatov, Dmitriy V., Ensley, Harry E., Cheng, Shih-Chin, Netea, Mihai G., Williams, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916545/
https://ncbi.nlm.nih.gov/pubmed/24344127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529131
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