Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke

NPP4 is a type I extracellular membrane protein on brain vascular endothelium inducing platelet aggregation via the hydrolysis of Ap3A, whereas NPP1 is a type II extracellular membrane protein principally present on the surface of chondrocytes that regulates tissue mineralization. To understand the...

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Detalhes bibliográficos
Main Authors: Albright, Ronald A., Ornstein, Deborah L., Cao, Wenxiang, Chang, William C., Robert, Donna, Tehan, Martin, Hoyer, Denton, Liu, Lynn, Stabach, Paul, Yang, Guangxiao, De La Cruz, Enrique M., Braddock, Demetrios T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916532/
https://ncbi.nlm.nih.gov/pubmed/24338010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505867
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