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Accumulation of coated vesicles bearing mannose 6-phosphate receptors for lysosomal enzymes in the Golgi region of I-cell fibroblasts.

The distribution of mannose 6-phosphate (Man6P) receptors for lysosomal enzymes was investigated in human normal and mucolipidosis II (I-cell) disease fibroblasts by light and electron microscopic immunocytochemistry. In normal fibroblasts whose lysosomal enzymes contain Man6P recognition markers re...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Brown, W J, Farquhar, M G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391652/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6147848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.16.5135
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