Early origin and pervasiveness of cellular heterogeneity in some malignant transformations.
Nontransformed BALB/3T3 cells were passaged weekly in monolayer culture on plastic dishes and aliquots were regularly assayed for colony production when suspended in agar. During several months of passaging, a single large colony arose once in the agar assay, and its constituent cells were isolated...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6591182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.16.5121 |
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