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Early origin and pervasiveness of cellular heterogeneity in some malignant transformations.

Nontransformed BALB/3T3 cells were passaged weekly in monolayer culture on plastic dishes and aliquots were regularly assayed for colony production when suspended in agar. During several months of passaging, a single large colony arose once in the agar assay, and its constituent cells were isolated...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autor principal: Rubin, H
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6591182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.16.5121
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