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Ciliary Genes Are Down-Regulated in Bronchial Tissue of Primary Ciliary Dyskinesia Patients

Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous disease characterized by recurrent respiratory tract infections, sinusitis, bronchiectasis and male infertility. The pulmonary phenotype in PCD is caused by the impaired motility of cilia in the respiratory epithelium, due to ultr...

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Detalhes bibliográficos
Main Authors: Geremek, Maciej, Ziętkiewicz, Ewa, Bruinenberg, Marcel, Franke, Lude, Pogorzelski, Andrzej, Wijmenga, Cisca, Witt, Michał
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916409/
https://ncbi.nlm.nih.gov/pubmed/24516614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088216
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