Transfer RNA mischarging mediated by a mutant Escherichia coli glutaminyl-tRNA synthetase.

We have isolated mutations in the Escherichia coli glnS gene encoding glutaminyl-tRNA synthetase [GlnS; L-glutamine:tRNAGln ligase (AMP-forming), EC 6.1.1.18] that give rise to gene products with altered specificity for tRNA and are designated "mischarging" enzymes. These were produced by...

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Bibliographic Details
Main Authors: Inokuchi, H, Hoben, P, Yamao, F, Ozeki, H, Söll, D
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC391640/
https://ncbi.nlm.nih.gov/pubmed/6382258
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