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Transfer RNA mischarging mediated by a mutant Escherichia coli glutaminyl-tRNA synthetase.

We have isolated mutations in the Escherichia coli glnS gene encoding glutaminyl-tRNA synthetase [GlnS; L-glutamine:tRNAGln ligase (AMP-forming), EC 6.1.1.18] that give rise to gene products with altered specificity for tRNA and are designated "mischarging" enzymes. These were produced by nitrosogua...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Inokuchi, H, Hoben, P, Yamao, F, Ozeki, H, Söll, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6382258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.16.5076
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