Herg K(+) Channel-Dependent Apoptosis and Cell Cycle Arrest in Human Glioblastoma Cells

Glioblastoma (GB) is associated with poor patient survival owing to uncontrolled tumor proliferation and resistance to apoptosis. Human ether-a-go-go-related gene K(+) channels (hERG; Kv11.1, KCNH2) are expressed in multiple cancer cells including GB and control cell proliferation and death. We hypo...

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Main Authors: Staudacher, Ingo, Jehle, Julian, Staudacher, Kathrin, Pledl, Hans-Werner, Lemke, Dieter, Schweizer, Patrick A., Becker, Rüdiger, Katus, Hugo A., Thomas, Dierk
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916397/
https://ncbi.nlm.nih.gov/pubmed/24516604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088164
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