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Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

Although two related species may have extremely similar phenotypes, the genetic networks underpinning this conserved biology may have diverged substantially since they last shared a common ancestor. This is termed Developmental System Drift (DSD) and reflects the plasticity of genetic networks. One...

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Auteurs principaux: Verster, Adrian J., Ramani, Arun K., McKay, Sheldon J., Fraser, Andrew G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916228/
https://ncbi.nlm.nih.gov/pubmed/24516395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004077
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