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Morpholino Treatment Improves Muscle Function and Pathology of Pitx1 Transgenic Mice

Paired-like homeodomain transcription factor 1 (PITX1) was proposed to be part of the disease mechanisms of facioscapulohumeral muscular dystrophy (FSHD). We generated a tet-repressible muscle-specific Pitx1 transgenic mouse model which develops phenotypes of muscular dystrophy after the PITX1 expre...

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Detalles Bibliográficos
Main Authors: Pandey, Sachchida Nand, Lee, Yi-Chien, Yokota, Toshifumi, Chen, Yi-Wen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916049/
https://ncbi.nlm.nih.gov/pubmed/24232919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.263
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