Intrathecal AAV Serotype 9-mediated Delivery of shRNA Against TRPV1 Attenuates Thermal Hyperalgesia in a Mouse Model of Peripheral Nerve Injury

Gene therapy for neuropathic pain requires efficient gene delivery to both central and peripheral nervous systems. We previously showed that an adenoassociated virus serotype 9 (AAV9) vector expressing short-hairpin RNA (shRNA) could suppress target molecule expression in the dorsal root ganglia (DR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hirai, Takashi, Enomoto, Mitsuhiro, Kaburagi, Hidetoshi, Sotome, Shinichi, Yoshida-Tanaka, Kie, Ukegawa, Madoka, Kuwahara, Hiroya, Yamamoto, Mariko, Tajiri, Mio, Miyata, Haruka, Hirai, Yukihiko, Tominaga, Makoto, Shinomiya, Kenichi, Mizusawa, Hidehiro, Okawa, Atsushi, Yokota, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916042/
https://ncbi.nlm.nih.gov/pubmed/24322332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.247
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados