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Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors.

Bronchial hyperresponsiveness to contractile agonists and nonspecific irritants is a characteristic feature of bronchial asthma. The mechanisms causing this hyperirritability are unknown. The existence of separate receptors for leukotrienes C4 and D4 (LTC4 and LTD4) has been demonstrated previously...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lee, T H, Austen, K F, Corey, E J, Drazen, J M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391604/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6087352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.15.4922
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