Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors.

Bronchial hyperresponsiveness to contractile agonists and nonspecific irritants is a characteristic feature of bronchial asthma. The mechanisms causing this hyperirritability are unknown. The existence of separate receptors for leukotrienes C4 and D4 (LTC4 and LTD4) has been demonstrated previously...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Lee, T H, Austen, K F, Corey, E J, Drazen, J M
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1984
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6087352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.15.4922
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