Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma

We have previously identified 1 241 regions of somatic copy number alterations (CNAs) in hepatocellular carcinoma (HCC). In the present study, we found that a novel recurrent focal amplicon, 1q24.1-24.2, targets the MPZL1 gene in HCC. Notably, there is a positive correlation between the expression l...

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Hlavní autoři: Jia, Deshui, Jing, Ying, Zhang, Zhenfeng, Liu, Li, Ding, Jie, Zhao, Fangyu, Ge, Chao, Wang, Qifeng, Chen, Taoyang, Yao, Ming, Li, Jinjun, Gu, Jianren, He, Xianghuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915911/
https://ncbi.nlm.nih.gov/pubmed/24296779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.158
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