Retrovirus-induced spongiform encephalopathy: the 3'-end long terminal repeat-containing viral sequences influence the incidence of the disease and the specificity of the neurological syndrome.

Using chimeric murine leukemia viruses (MuLVs) constructed in vitro with parental viral genomes from the neurotropic Cas-BR-E MuLV and the nonneurotropic amphotropic 4070-A MuLV, we previously mapped the paralysis-inducing determinant of Cas-BR-E MuLV within a pol-env region. To assess the role of t...

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Autores principales: DesGroseillers, L, Rassart, E, Robitaille, Y, Jolicoeur, P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC391529/
https://ncbi.nlm.nih.gov/pubmed/3866255
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