The tandem direct repeats within the long terminal repeat of murine leukemia viruses are the primary determinant of their leukemogenic potential.

To map the viral sequences encoding the leukemogenic determinant(s) of nondefective murine leukemia viruses (MuLVs), we constructed chimeric viral genomes in vitro between cloned viral DNAs from the highly leukemogenic Gross passage A (Gross A) MuLV and from the related nonleukemogenic BALB/c N-trop...

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Bibliographic Details
Published in:J Virol
Main Authors: DesGroseillers, L, Jolicoeur, P
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6092722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.52.3.945-952.1984
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