Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments.

cGMP opens cation-selective channels when applied to the cytoplasmic side of excised patches of membrane from retinal rod outer segments (ROS). If the light-sensitive channel in intact rods is gated only by cGMP, it should be possible to find a hydrolysis-resistant analog of cGMP that blocks the nor...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zimmerman, A L, Yamanaka, G, Eckstein, F, Baylor, D A, Stryer, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8813
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!