Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.
We describe a transgenic mouse line carrying the cre transgene under the control of the adenovirus EIIa promoter that targets expression of the Cre recombinase to the early mouse embryo. To assess the ability of this recombinase to excise loxP-flanked DNA sequences at early stages of development, we...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39152/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650183/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5860 |
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