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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

We describe a transgenic mouse line carrying the cre transgene under the control of the adenovirus EIIa promoter that targets expression of the Cre recombinase to the early mouse embryo. To assess the ability of this recombinase to excise loxP-flanked DNA sequences at early stages of development, we...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Lakso, M, Pichel, J G, Gorman, J R, Sauer, B, Okamoto, Y, Lee, E, Alt, F W, Westphal, H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5860
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