Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling

BACKGROUND: Cancer-associated fibroblasts (CAFs) activated by tumour cells are the predominant type of stromal cells in breast cancer tissue. The reciprocal effect of CAFs on breast cancer cells and the underlying molecular mechanisms are not fully characterised. METHODS: Stromal fibroblasts were is...

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Detalhes bibliográficos
Main Authors: Yu, Y, Xiao, C-H, Tan, L-D, Wang, Q-S, Li, X-Q, Feng, Y-M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915130/
https://ncbi.nlm.nih.gov/pubmed/24335925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.768
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