Fucosylated TGF-β receptors transduces a signal for epithelial–mesenchymal transition in colorectal cancer cells

BACKGROUND: Transforming growth factor-β (TGF-β) is a major inducer of epithelial–mesenchymal transition (EMT) in different cell types. TGF-β-mediated EMT is thought to contribute to tumour cell spread and metastasis. Sialyl Lewis antigens synthesised by fucosyltransferase (FUT) 3 and FUT6 are highl...

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Main Authors: Hirakawa, M, Takimoto, R, Tamura, F, Yoshida, M, Ono, M, Murase, K, Sato, Y, Osuga, T, Sato, T, Iyama, S, Miyanishi, K, Takada, K, Hayashi, T, Kobune, M, Kato, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887298/
https://ncbi.nlm.nih.gov/pubmed/24253505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.699
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