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TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis
BACKGROUND: TMPRSS4 is a membrane-anchored protease involved in cell migration and invasion in different cancer types including lung cancer. TMPRSS4 expression is increased in NSCLC and its inhibition through shRNA reduces lung metastasis. However, molecular mechanisms leading to the protumorigenic...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915125/ https://ncbi.nlm.nih.gov/pubmed/24434435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.761 |
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