TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis

BACKGROUND: TMPRSS4 is a membrane-anchored protease involved in cell migration and invasion in different cancer types including lung cancer. TMPRSS4 expression is increased in NSCLC and its inhibition through shRNA reduces lung metastasis. However, molecular mechanisms leading to the protumorigenic...

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Bibliographic Details
Main Authors:	Larzabal, L, de Aberasturi, A L, Redrado, M, Rueda, P, Rodriguez, M J, Bodegas, M E, Montuenga, L M, Calvo, A
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2014
Subjects:	Molecular Diagnostics
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3915125/ https://ncbi.nlm.nih.gov/pubmed/24434435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.761
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TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis

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