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TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis
BACKGROUND: TMPRSS4 is a membrane-anchored protease involved in cell migration and invasion in different cancer types including lung cancer. TMPRSS4 expression is increased in NSCLC and its inhibition through shRNA reduces lung metastasis. However, molecular mechanisms leading to the protumorigenic...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915125/ https://ncbi.nlm.nih.gov/pubmed/24434435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.761 |
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