TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis

BACKGROUND: TMPRSS4 is a membrane-anchored protease involved in cell migration and invasion in different cancer types including lung cancer. TMPRSS4 expression is increased in NSCLC and its inhibition through shRNA reduces lung metastasis. However, molecular mechanisms leading to the protumorigenic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Larzabal, L, de Aberasturi, A L, Redrado, M, Rueda, P, Rodriguez, M J, Bodegas, M E, Montuenga, L M, Calvo, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Molecular Diagnostics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915125/
https://ncbi.nlm.nih.gov/pubmed/24434435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.761
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