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Current view on the functional regulation of the neuronal K(+)-Cl(−) cotransporter KCC2
In the mammalian central nervous system (CNS), the inhibitory strength of chloride (Cl(−))-permeable GABA(A) and glycine receptors (GABA(A)R and GlyR) depends on the intracellular Cl(−) concentration ([Cl(−)](i)). Lowering [Cl(−)](i) enhances inhibition, whereas raising [Cl(−)](i) facilitates neuron...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915100/ https://ncbi.nlm.nih.gov/pubmed/24567703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00027 |
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