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Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration
During DNA repair by homologous recombination (HR), DNA synthesis copies information from a template DNA molecule. Multiple DNA polymerases have been implicated in repair-specific DNA synthesis(1)–(3), but it has remained unclear whether a DNA helicase is involved in this reaction. A good candidate...
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Autors principals: | , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915060/ https://ncbi.nlm.nih.gov/pubmed/24025768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12585 |
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