Mutational Analyses of Multiple Oncogenic Pathways in Intraductal Papillary Mucinous Neoplasms of the Pancreas

OBJECTIVE: There is much accumulated evidence that EGFR, HER2, and their downstream signaling pathway members such as KRAS, BRAF, and PIK3CA are strongly implicated in cancer development and progression. Recently, mutations in the kinase domains of EGFR and HER2, associated with increased sensitivit...

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Autori principali: Schönleben, Frank, Allendorf, John D., Qiu, Wanglong, Li, Xiaojun, Ho, Daniel J., Ciau, Nancy T., Fine, Robert L., Chabot, John A., Remotti, Helen E., Su, Gloria H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915029/
https://ncbi.nlm.nih.gov/pubmed/18376308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e318158a4d2
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