Loss of PTEN expression is associated with poor prognosis in patients with intraductal papillary mucinous neoplasms of the pancreas

PURPOSE: Previously, we reported PIK3CA gene mutations in high-grade intraductal papillary mucinous neoplasms (IPMN). However, the contribution of phosphatidylinositol-3 kinase pathway (PI3K) dysregulation to pancreatic carcinogenesis is not fully understood and its prognostic value unknown. We inve...

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Detalhes bibliográficos
Main Authors: Garcia-Carracedo, Dario, Turk, Andrew T., Fine, Stuart A., Akhavan, Nathan, Tweel, Benjamin C., Parsons, Ramon, Chabot, John A., Allendorf, John D., Genkinger, Jeanine M., Remotti, Helen E., Su, Gloria H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915026/
https://ncbi.nlm.nih.gov/pubmed/24132918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0624
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