A Regulatory Feedback Loop between HIF-1α and PIM2 in HepG2 Cells

To survive under hypoxic conditions, cancer cells remodel glucose metabolism to support tumor progression. HIF transcription factor is essential for cellular response to hypoxia. The underlying mechanism how HIF is constitutively activated in cancer cells remains elusive. In the present study, we ch...

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Detalhes bibliográficos
Main Authors: Yu, Zhenhai, Zhao, Xiaoping, Ge, Yingying, Zhang, Teng, Huang, Liangqian, Zhou, Xiang, Xie, Lei, Liu, Jianjun, Huang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914973/
https://ncbi.nlm.nih.gov/pubmed/24505470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088301
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