Combination of (1)H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats

BACKGROUND: Coptidis Rhizome (CR), widely applied to treat with heat and toxicity, is one of the most commonly used traditional Chinese medicine (TCM), however, an extensive dosage can induce toxicity. Diarrhea is one of the most frequent side effects of CR treatment. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalhes bibliográficos
Main Authors: Zhou, Yuting, Liao, Qiongfeng, Lin, Manna, Deng, Xuejiao, Zhang, Peiting, Yao, Meicun, Zhang, Lei, Xie, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914965/
https://ncbi.nlm.nih.gov/pubmed/24505462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088281
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