Role of an RNA cleavage/poly(A) addition site in the production of membrane-bound and secreted IgM mRNA.
The switch from membrane-bound to secreted IgM is accomplished by producing alternative forms of mRNA from a single mu heavy-chain gene. This process might be controlled at any of three steps--transcription termination, RNA splicing, or RNA cleavage/poly(A) addition. To distinguish between these pos...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1985
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8658 |
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