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Role of an RNA cleavage/poly(A) addition site in the production of membrane-bound and secreted IgM mRNA.

The switch from membrane-bound to secreted IgM is accomplished by producing alternative forms of mRNA from a single mu heavy-chain gene. This process might be controlled at any of three steps--transcription termination, RNA splicing, or RNA cleavage/poly(A) addition. To distinguish between these pos...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Danner, D, Leder, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8658
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