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Isolation and characterization of anti-monosialoganglioside monoclonal antibody 19-9 class-switch variants.

Three different monoclonal antibody isotypes, IgG1, IgG2b, and IgG2a, were derived by selection of isotype-switch variants from the CO-19-9 hybridoma. All three antibodies retained their binding specificities and affinities and bound to the same epitope--as defined by the anti-idiotype analysis. Ava...

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Detalhes bibliográficos
Main Authors: Steplewski, Z, Spira, G, Blaszczyk, M, Lubeck, M D, Radbruch, A, Illges, H, Herlyn, D, Rajewsky, K, Scharff, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391494/
https://ncbi.nlm.nih.gov/pubmed/2934735
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