A Novel Cellular Senescence Gene, SENEX, Is Involved in Peripheral Regulatory T Cells Accumulation in Aged Urinary Bladder Cancer

Regulatory T cells (Tregs) play an essential role in sustaining self-tolerance and immune homeostasis. Despite many studies on the correlation between Tregs accumulation and age, or malignancies, the related mechanism hasn’t been well explored. To find out the mechanism of Tregs accumulation in aged...

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Autori principali: Chen, Tianping, Wang, Huiping, Zhang, Zhiqiang, Li, Qing, Yan, Kaili, Tao, Qianshan, Ye, Qianling, Xiong, Shudao, Wang, Yiping, Zhai, Zhimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914842/
https://ncbi.nlm.nih.gov/pubmed/24505313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087774
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