A Novel Cellular Senescence Gene, SENEX, Is Involved in Peripheral Regulatory T Cells Accumulation in Aged Urinary Bladder Cancer

Regulatory T cells (Tregs) play an essential role in sustaining self-tolerance and immune homeostasis. Despite many studies on the correlation between Tregs accumulation and age, or malignancies, the related mechanism hasn’t been well explored. To find out the mechanism of Tregs accumulation in aged...

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Detalhes bibliográficos
Main Authors: Chen, Tianping, Wang, Huiping, Zhang, Zhiqiang, Li, Qing, Yan, Kaili, Tao, Qianshan, Ye, Qianling, Xiong, Shudao, Wang, Yiping, Zhai, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914842/
https://ncbi.nlm.nih.gov/pubmed/24505313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087774
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