A Novel Cellular Senescence Gene, SENEX, Is Involved in Peripheral Regulatory T Cells Accumulation in Aged Urinary Bladder Cancer

Regulatory T cells (Tregs) play an essential role in sustaining self-tolerance and immune homeostasis. Despite many studies on the correlation between Tregs accumulation and age, or malignancies, the related mechanism hasn’t been well explored. To find out the mechanism of Tregs accumulation in aged...

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Opis bibliograficzny
Główni autorzy: Chen, Tianping, Wang, Huiping, Zhang, Zhiqiang, Li, Qing, Yan, Kaili, Tao, Qianshan, Ye, Qianling, Xiong, Shudao, Wang, Yiping, Zhai, Zhimin
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914842/
https://ncbi.nlm.nih.gov/pubmed/24505313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087774
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