Real-Time, Transcranial Monitoring of Safe Blood-Brain Barrier Opening in Non-Human Primates

The delivery of drugs to specific neural targets faces two fundamental problems: (1) most drugs do not cross the blood-brain barrier, and (2) those that do, spread to the entire brain. To date, there exists only one non-invasive methodology with the potential to solve these problems: selective blood...

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Bibliografiske detaljer
Main Authors: Marquet, Fabrice, Teichert, Tobias, Wu, Shih-Ying, Tung, Yao-Sheng, Downs, Matthew, Wang, Shutao, Chen, Cherry, Ferrera, Vincent, Konofagou, Elisa E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914779/
https://ncbi.nlm.nih.gov/pubmed/24505248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084310
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