Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis

The angiotensin II type 1 receptor (AT1R) blocker losartan ameliorates rheumatoid arthritis (RA) in an experimental model. In RA, AT2R mainly opposes AT1R, but the mechanism by which this occurs still remains obscure. In the present study, we investigated the role of AT2R in the treatment of rats wi...

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Bibliografiske detaljer
Main Authors: Wang, Di, Hu, Shanshan, Zhu, Jie, Yuan, Jun, Wu, Jingjing, Zhou, Aiwu, Wu, Yujing, Zhao, Wendi, Huang, Qiong, Chang, Yan, Wang, Qingtong, Sun, Wuyi, Wei, Wei
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons Ltd 2013
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914644/
https://ncbi.nlm.nih.gov/pubmed/24112447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12128
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