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Feedback Regulation of SIN by Etd1 and Rho1 in Fission Yeast

In fission yeast, the septation initiation network (SIN) is thought to promote cytokinesis by downstream activation of Rho1, a conserved GTPase that controls cell growth and division. Here we show that Etd1 and PP2A-Pab1, antagonistic regulators of SIN, are Rho1 regulators. Our genetic and biochemic...

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Detalhes bibliográficos
Main Authors: Alcaide-Gavilán, María, Lahoz, Aurelia, Daga, Rafael R., Jimenez, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914619/
https://ncbi.nlm.nih.gov/pubmed/24336750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.155218
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