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Regulation of DNA Replication Machinery by Mrc1 in Fission Yeast

Faithful replication of chromosomes is crucial to genome integrity. In yeast, the ORC binds replication origins throughout the cell cycle. However, Cdc45 binds these before S-phase, and, during replication, it moves along the DNA with MCM helicase. When replication progression is inhibited, checkpoi...

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Main Authors: Nitani, Naoki, Nakamura, Ken-ichi, Nakagawa, Chie, Masukata, Hisao, Nakagawa, Takuro
Formato: Artigo
Idioma:Inglês
Publicado: Copyright © 2006 by the Genetics Society of America 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569812/
https://ncbi.nlm.nih.gov/pubmed/16849602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060053
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