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Regulation of DNA Replication Machinery by Mrc1 in Fission Yeast
Faithful replication of chromosomes is crucial to genome integrity. In yeast, the ORC binds replication origins throughout the cell cycle. However, Cdc45 binds these before S-phase, and, during replication, it moves along the DNA with MCM helicase. When replication progression is inhibited, checkpoi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569812/ https://ncbi.nlm.nih.gov/pubmed/16849602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060053 |
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