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Crosslinked Linear Polyethyleneimine Enhances Delivery of DNA to the Cytoplasm

Crosslinked polyethylenimines (PEIs) have been frequently examined over the past decade since they can maintain the transfection efficiency of commercially available, 25k branched PEI, but exhibit less cytotoxicity. The argument is often made that the degradability of such polymers, generally synthe...

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Detalhes bibliográficos
Main Authors: Bonner, Daniel K., Zhao, Xiaoyong, Buss, Hilda, Langer, Robert, Hammond, Paula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914540/
https://ncbi.nlm.nih.gov/pubmed/22995755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.09.004
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