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Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5
The involvement of nitric oxide (NO) and cyclic GMP (cGMP) in neurogenesis has been progressively unmasked over the last decade. Phosphodiesterase 5 (PDE5) specifically degrades cGMP and is highly abundant in the mammalian brain. Inhibition of cGMP hydrolysis by blocking PDE5 is a possible strategy...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Publishing Corporation
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914480/ https://ncbi.nlm.nih.gov/pubmed/24550991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/878397 |
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