Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells.

We have placed human insulin receptor cDNA into a vector under the control of the simian virus 40 (SV40) early promoter and tested its function by transient expression in microinjected Xenopus oocytes and by expression in stably transformed CHO cells. The precursor and the alpha and beta subunits of...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ebina, Y, Edery, M, Ellis, L, Standring, D, Beaudoin, J, Roth, R A, Rutter, W J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3906655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.8014
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