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Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA.

Purine residues located within regions of DNA that have the potential to form left-handed Z-helical structures are modified preferentially by diethyl pyrocarbonate; this hyperreactivity is dependent on the degree of negative superhelicity of the circular DNA molecules. As negative superhelical densi...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Herr, W
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1985
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3865212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.8009
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