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Amplification of DNA sequences in human multidrug-resistant KB carcinoma cells.

Four KB carcinoma cell lines selected independently for resistance to either colchicine, adriamycin, or vinblastine were studied. All cell lines showed high levels of resistance to the selecting drug and cross-resistance to the other drugs and to actinomycin D. Double-minute chromosomes could be ide...

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Autors principals: Fojo, A T, Whang-Peng, J, Gottesman, M M, Pastan, I
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC391393/
https://ncbi.nlm.nih.gov/pubmed/3865187
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