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Digital-Direct-RT-PCR: a sensitive and specific method for quantification of CTC in patients with cervical carcinoma

The detection of circulating tumour cells (CTC) in cancer patients may be useful for therapy monitoring and prediction of relapse. A sensitive assay based on HPV-oncogene transcripts which are highly specific for cervical cancer cells was established. The Digital-Direct-RT-PCR (DD-RT-PCR) combines F...

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Detalhes bibliográficos
Main Authors: Pfitzner, Claudia, Schröder, Isabel, Scheungraber, Cornelia, Dogan, Askin, Runnebaum, Ingo Bernhard, Dürst, Matthias, Häfner, Norman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913920/
https://ncbi.nlm.nih.gov/pubmed/24496006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03970
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